Glycopyrrolate Mnemonic
Glyco’s Pretty Reliable At Stopping Secretions
Gastrointestinal ulcers
Preoperative to reduce saliva
Reduce drooling
Anesthetic adjunct to prevent Neostigmine side effects
Stopping excessive sweating (hyperhidrosis)
Here are some key points about Glycopyrrolate that might be useful for your board exam review:
Classification: Glycopyrrolate is an anticholinergic (anti-muscarinic) drug.
Mechanism of Action: It works by blocking muscarinic receptors, thereby inhibiting the action of acetylcholine on these receptors.
Clinical Uses:
- Preoperative Use: Reduces salivation and respiratory secretions.
- Reversal of Neuromuscular Blockade: Used in combination with cholinesterase inhibitors to reverse the effects of non-depolarizing neuromuscular blockers.
- Peptic Ulcer Disease: Adjunctive management to reduce gastric secretions.
Pharmacokinetics:
- Onset of Action: Rapid, typically within minutes when given intravenously.
- Duration of Action: Lasts for several hours.
- Elimination: Primarily excreted unchanged in the urine.
Side Effects: Common side effects include dry mouth, blurred vision, constipation, and urinary retention.
Contraindications: Should not be used in patients with glaucoma, myasthenia gravis, or obstructive uropathy.
For more anesthesiology mnemonics check this mnemonic book.
This post covers the points you need to know for your board exams as well as for teaching residents on the daily rounds. Medical professionals can't use the information here to treat their patients nor people can use the information her to treat themselves. If you are having any medical issues, contact your local emergency services or your primary care provider. Please refer to your doctor for medical advice.