Fentanyl Mnemonic
FENTANYL
Fentanyl
Extremely potent opioid
Narcotic for anesthesia induction
Transdermal patches for chronic pain
Agonist at mu opioid receptors
Not for use with uncontrolled machinery
Yields sedation and respiratory depression
Lozenges for breakthrough cancer pain
Here are some key points about Fentanyl that might be useful for your board exam review:
Classification: Fentanyl is a potent synthetic opioid analgesic.
Potency: It is approximately 100 times more potent than morphine.
Mechanism of Action: Fentanyl works by binding to the mu-opioid receptors in the brain and spinal cord, leading to analgesia and sedation.
Clinical Uses:
- Pain Management: Used for severe pain, such as in cancer patients or post-surgical pain.
- Anesthesia: Commonly used as an adjunct to anesthesia for its analgesic properties.
- Chronic Pain: Available in transdermal patches for long-term pain management.
Pharmacokinetics:
- Onset of Action: Rapid, typically within minutes when administered intravenously.
- Duration of Action: Short, lasting about 30-60 minutes when given intravenously.
- Metabolism: Primarily metabolized in the liver by the cytochrome P450 enzyme system, specifically CYP3A4.
- Excretion: Excreted mainly in the urine.
Side Effects: Common side effects include respiratory depression, constipation, nausea, and sedation.
Special Considerations:
- Risk of Overdose: Due to its high potency, there is a significant risk of overdose, which can be fatal.
- Tolerance and Dependence: Prolonged use can lead to tolerance, dependence, and addiction.
For more anesthesiology mnemonics check this mnemonic book.
This post covers the points you need to know for your board exams as well as for teaching residents on the daily rounds. Medical professionals can't use the information here to treat their patients nor people can use the information her to treat themselves. If you are having any medical issues, contact your local emergency services or your primary care provider. Please refer to your doctor for medical advice.