Etomidate Mnemonic
ETOMIDATE
Efficient with peak action 1 minute
Tranquilizer
Onset is quick with onset 30 to 60 seconds
Minimal cardiovascular effects
Inhibits adrenal steroidogenesis (off-label in Cushing's)
Doesn’t cause pain on injection
Administer Fentanyl to prevent myoclonus
Trigger for myoclonus
Excellent for hemodynamically unstable patients
Here are some key points about Etomidate that might be useful for your board exam review:
Classification: Etomidate is a short-acting intravenous anesthetic agent.
Mechanism of Action: It enhances the activity of the neurotransmitter GABA at the GABA-A receptor, leading to sedation and hypnosis.
Clinical Uses:
- Induction of Anesthesia: Commonly used for the induction of general anesthesia.
- Rapid Sequence Intubation (RSI): Preferred in emergency settings due to its hemodynamic stability.
Pharmacokinetics:
- Onset of Action: Rapid, typically within 30-60 seconds.
- Duration of Action: Short, lasting about 3-5 minutes.
- Metabolism: Primarily metabolized by hepatic microsomal enzymes and plasma Esterases.
Side Effects:
- Myoclonus: Involuntary muscle movements, which can be attenuated by premedication with opioids.
- Adrenal Suppression: Inhibits 11-beta-hydroxylase, leading to transient adrenal suppression.
- Nausea and Vomiting: Common post-operative side effects.
Hemodynamic Stability: Minimal effects on cardiovascular and respiratory systems, making it suitable for patients with cardiovascular instability.
For more anesthesiology mnemonics check this mnemonic book.
This post covers the points you need to know for your board exams as well as for teaching residents on the daily rounds. Medical professionals can't use the information here to treat their patients nor people can use the information her to treat themselves. If you are having any medical issues, contact your local emergency services or your primary care provider. Please refer to your doctor for medical advice.